Clarithromycin
Clarithromycin

2.04
Clarithromycin is a macrolide antibiotic utilized for the treatment of a broad range of bacterial respiratory and skin infections.


Ingredient
Category
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Clarithromycin
Reference Brand
Klacid
Product Origin
Generic Product
Reference Manufacturer
Abbott
Product Form
Tablet, Suspension
Regulatory Classification
Rx
Primary Category
Antibiotics
Product Category
Macrolide
Pharmacological Class
Macrolide antibiotic
Clinical Indications
Bacterial infections, Respiratory infections, Skin infections
Manufacturer Description
Clarithromycin is a macrolide antibiotic utilized for the treatment of a broad range of bacterial respiratory and skin infections.
Mechanism of Action
Clarithromycin inhibits bacterial protein synthesis by binding to the bacterial ribosome, preventing the bacteria from multiplying and clearing the infection.
Route of Administration
Oral
Onset Time
1–2 hours
Duration
12 hours
Contraindications
Hypersensitivity to macrolides
Severe Adverse Events
Arrhythmia, Hearing loss
Common Side Effects
Diarrhea, Nausea
Uncommon Side Effects
Abdominal pain, Disturbed taste
Drug Interactions
Statins, Warfarin
Pregnancy Safety Warnings
Consult doctor before use.
Storage Guidelines
Store at room temperature away from light.
Related Products
Azithromycin, Erythromycin

Clarithromycin FAQ

Can I take clarithromycin with antacids?

Clarithromycin’s absorption is not significantly affected by antacids, so they can be taken together. However, if you are using a magnesium- or aluminum-containing antacid, spacing the doses by at least two hours may improve tolerance.

What should I do if I develop a rash while on clarithromycin?

A rash may indicate an allergic reaction. Discontinue the medication and seek medical evaluation promptly, especially if the rash is widespread, itchy, or accompanied by swelling or breathing difficulty.

Is clarithromycin safe for travel to countries with high rates of antibiotic-resistant bacteria?

Clarithromycin remains effective against many common respiratory pathogens, but resistance rates vary regionally. Consult a travel health clinic before departure to determine if a different antibiotic is recommended for your itinerary.

How can I identify genuine clarithromycin tablets?

Authentic tablets are typically round, film-coated, and imprint with the dosage strength (e.g., “250 mg” or “500 mg”) along with the manufacturer’s logo. Verify packaging details and expiration dates against the pharmacy receipt.

Will clarithromycin affect my blood test results?

Clarithromycin can cause mild, transient elevations in liver enzymes (ALT, AST). If you are undergoing routine blood work, inform your clinician about the medication so results can be interpreted accurately.

Can clarithromycin interact with herbal supplements?

Yes. Herbal products such as St. John’s wort induce CYP3A4 and may reduce clarithromycin’s effectiveness. Discuss any supplements with your healthcare provider before starting therapy.

Is it necessary to avoid dairy products while taking clarithromycin?

No specific restriction exists for dairy. Clarithromycin can be taken with or without food, including milk or cheese, without compromising its absorption.

Symptoms may include jaundice (yellowing of skin or eyes), dark urine, abdominal pain, and unexplained fatigue. If these occur, seek medical attention immediately.

Does clarithromycin increase the risk of heart rhythm problems?

Clarithromycin can prolong the QT interval, especially when combined with other QT-prolonging agents or in patients with existing cardiac conditions. An ECG is advisable before initiating therapy in high-risk individuals.

How long should I store unused clarithromycin tablets?

Tablets retain potency up to the printed expiration date when stored at room temperature, away from moisture. Do not use tablets past this date, and discard any that appear discolored or damaged.

Targeted Bacterial Growth Inhibition

Interfering with bacterial protein synthesis, Clarithromycin functions as a macrolide class antibiotic. This compound exerts its effect by binding to the 50S ribosomal subunit of susceptible microorganisms, thereby preventing the translation of essential proteins needed for bacterial survival and replication.

Primarily utilized for its broad-spectrum capability against various pathogens, this active substance is a cornerstone in addressing localized and systemic infections throughout Hong Kong. Clinicians frequently integrate it into treatment regimens for respiratory tract infections and specific dermatological conditions.

Formulations containing this active compound, such as Klacid and various generic alternatives, allow for flexible administration in both hospital and community settings within the territory. As an active pharmaceutical ingredient, it exists in multiple delivery forms to suit the specific requirements of the infection being treated.

Clinical Delivery Systems

The availability of Clarithromycin in Hong Kong ranges from standard oral tablets to modified-release formulations and oral suspensions. These diverse forms allow healthcare providers to select an administration route that aligns with the patient's individual clinical profile and the severity of the infection.

Generics provide an identical chemical formulation to established brands, meeting the same quality standards as set by the Pharmacy and Poisons Board of Hong Kong. Whether a patient receives a branded or generic version, the underlying active ingredient remains consistent in its chemical structure and pharmacological action.

Primary Therapeutic Indications

  • Respiratory tract infections, including pharyngitis and pneumonia, where bacterial clearance is required.
  • Skin and soft tissue infections caused by sensitive organisms.
  • Acute otitis media, involving the inflammation of the middle ear space.
  • Eradication of Helicobacter pylori when combined with other elements to address gastric ulcer-related symptoms.
  • Disseminated mycobacterial infections in specific immunocompromised populations.

Mechanism of Action

Working within the cell, the substance disrupts the machinery that bacteria use to create protein. Without these proteins, bacteria cannot grow or distribute themselves further into the body tissues. By halting this growth, the immune system is granted a window to manage and clear the remaining pathogens naturally.

Safety Considerations

Common Reactions

Patients may occasionally experience temporary gastrointestinal changes such as abdominal discomfort, nausea, or a metallic taste sensation. These patterns are generally mild and diminish as the body adjusts to the active ingredient.

Serious Reactions

Immediate medical attention is necessary if severe allergic responses appear, such as difficulty breathing, swelling of the face or throat, or the sudden onset of a skin rash. Additionally, unexpected changes in heart rhythm or persistent liver-related symptoms should be treated as indicators requiring prompt assessment.

Contraindications

Individuals with a documented hypersensitivity to macrolide antibiotics should avoid this compound. Furthermore, those with specific electrolyte imbalances, such as low potassium or magnesium levels, or individuals managing severe hepatic impairment must proceed with caution.

Interaction Awareness

The substance has the potential to influence the way the body processes other chemical compounds, which may lead to concentration changes in the bloodstream. Substances such as specific cardiovascular agents, anticoagulants, or enzyme-affecting agents may generate interactions. Always verify the medication insert for a comprehensive list of known interactions pertinent to your specific formulation.

Guidelines for Storage and Usage

Proper management of this medication necessitates storing it at a consistent room temperature, away from moisture and direct heat sources. Treatment duration varies significantly based on the diagnosis, ranging from short-term acute care to longer-term management. Because individual requirements differ, patients must note that standard dosing protocols are determined by clinical need. For detailed usage, dosing, and administration, refer to the specific medication's clinical information.

Glossary of Terms

Macrolide
A category of antibiotics characterized by a large macrocyclic lactone ring that inhibits bacterial protein production.
Ribosomal subunit
The biological machinery inside a cell responsible for assembling proteins from amino acids.
Pathogen
A biological agent, such as a bacterium, that has the potential to cause illness or infection within a host organism.

Clinical Safety and Accountability

This document provides a general educational overview of Clarithromycin and should not be interpreted as professional medical advice. Diverse formulations of medications like Klacid vary in concentration, excipient composition, and regulatory instruction. The publisher assumes no liability for the application of this information in clinical practice. Patients must review their specific medication labeling for accurate usage guidance and consult a licensed healthcare professional in Hong Kong to address individual health circumstances and medicinal needs.

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