Cyclomune
Cyclomune

40.46
Cyclomune is a prescription eye drop utilized to increase tear production in patients whose tear production is suppressed due to ocular inflammation associated with keratoconjunctivitis sicca (dry eye).


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Cyclosporine
Product Origin
Generic Brand
Product Manufacturer
Sun Pharma
Product Form
Eye Drops
Regulatory Classification
Rx
Primary Category
Ophthalmic Care, Autoimmune Support
Product Category
Immunomodulator
Pharmacological Class
Calcineurin Inhibitor
Clinical Indications
Dry eye syndrome, Keratoconjunctivitis sicca
Manufacturer Description
Cyclomune is a prescription eye drop utilized to increase tear production in patients whose tear production is suppressed due to ocular inflammation associated with keratoconjunctivitis sicca (dry eye).
Mechanism of Action
Cyclosporine is a targeted immunomodulator that inhibits local T-cell activation in the conjunctiva and lacrimal glands, thereby reducing inflammation and restoring natural tear production.
Route of Administration
Ophthalmic
Onset Time
Several weeks of use
Duration
Ongoing
Contraindications
Ocular infections
Severe Adverse Events
Ocular irritation, Foreign body sensation
Common Side Effects
Stinging, Itching
Uncommon Side Effects
Redness, Blurred vision
Pregnancy Safety Warnings
Consult a doctor.
Age Restrictions
Not for children.
Storage Guidelines
Store at room temperature away from light.
Related Products
Restasis

Cyclomune FAQ

Can I travel with Cyclomune in my hand luggage?

Yes. Cyclomune is classified as a prescription ophthalmic medication, not a controlled substance, so it can be carried in hand luggage. Keep the bottle in its original packaging and present the prescription label if requested at security.

How does Cyclomune differ from other cyclosporine eye drops on the market?

While all cyclosporine ophthalmic solutions share the same active ingredient, formulation differences (e.g., preservative type, vehicle viscosity) can affect tolerability. Cyclomune’s bottle format and available strengths (0.05 % and 0.1 %) provide flexibility for clinicians to tailor therapy based on disease severity.

What does the bottle of Cyclomune look like?

Cyclomune is supplied in a clear, opaque-white ophthalmic bottle with a dropper tip. The label displays the product name, concentration (0.05 % or 0.1 %), and regulatory information required in Hong Kong.

Do I need to avoid contact lens wear while using Cyclomune?

It is advisable to remove contact lenses before instilling the drops and wait at least 15 minutes before reinserting them. This reduces the risk of lens contamination and ensures optimal drug absorption.

Is Cyclomune subject to drug testing for athletes?

Cyclosporine is listed on the World Anti-Doping Agency (WADA) prohibited list when used systemically. Topical ocular use is generally considered a low-risk route, but athletes should disclose all medications to their sports governing body.

What are the key clinical trials that supported Cyclomune’s approval?

Pivotal Phase III studies demonstrated that twice-daily cyclosporine ophthalmic solution improved corneal staining scores and patient-reported symptoms compared with placebo. These trials formed the basis for regulatory approval for dry eye disease.

Can Cyclomune be stored in a refrigerator to prolong shelf life?

No. Storing the bottle at temperatures below room temperature can alter the solution’s viscosity and potency. Keep it at ambient conditions as indicated on the label.

How long after opening should I discard the bottle?

After opening, the solution should be discarded after 30 days to minimize the risk of microbial growth, even if the printed expiration date is later.

Will using Cyclomune affect my vision temporarily after each dose?

A brief period of blurred vision or visual “cloudiness” can occur for a few minutes after instillation. This is normal and typically resolves without intervention.

Why is the 0.1 % strength sometimes chosen over the 0.05 %?

The higher concentration may be prescribed for patients with more severe dry-eye signs or those who have not responded adequately to the lower strength. The clinician decides based on clinical assessment and tolerability.

Modulating Ocular Inflammation

Suppression of the immune system within the ocular surface allows Cyclomune to address chronic conditions characterized by inadequate tear production. By acting as a topical immunomodulator, this substance helps reduce the cellular markers associated with persistent irritation and dryness.

As a lipid-based formulation, this active compound is structured to increase the moisture-retaining capacity of the eye. It functions specifically to mitigate the underlying inflammation that often halts natural tear flow, assisting patients in maintaining ocular comfort throughout the day.

This ingredient is commonly synthesized into ophthalmic emulsion preparations. It is designed for gradual incorporation into the patient's daily routine, focusing on sustained management of ocular health rather than immediate, fleeting relief.

Formulation and Availability in Hong Kong

Cyclomune is utilized in ophthalmic emulsions which are widely accessible through local pharmacies and clinics in Hong Kong. These preparations are typically presented as single-use, preservative-free containers, ensuring that the integrity of the active ingredient remains stable throughout its shelf life.

In the Hong Kong medical landscape, patients may encounter various branded versions or standardized generic equivalents of these eye drops. Regardless of the specific brand name appearing on the packaging, the active component remains consistent in its chemical delivery, adhering to regional standards for ophthalmological preparations.

Areas of Therapeutic Focus

The application of this compound is generally oriented toward patients experiencing significant discomfort due to diminished lubricant production in the eyes. It is specifically aimed at addressing the following scenarios:

  • Chronic keratoconjunctivitis sicca manifesting as persistent grittiness or burning.
  • Inflammatory responses that prevent the healthy function of tear-producing glands.
  • Ocular surface dryness resulting from long-term exposure to dry environments or air conditioning.
  • Discomfort cycles where inflammation creates a feedback loop, further reducing moisture levels.

Biological Interaction with Ocular Tissues

When applied to the eye, the substance travels to the lacrimal glands to assist in the regulation of immune signaling. It works by interfering with the activation of T-cells, which are often the primary drivers of localized inflammatory responses on the eye surface.

By minimizing these signaling proteins, the compound encourages the tear glands to resume their natural secretory function. This shift helps to normalize the ocular surface environment, allowing the eyes to maintain a more consistent and healthy moisture film.

Safety Profile

Common Reactions

Patients may occasionally notice transient stinging or a temporary burning sensation upon the application of the drops. These sensations are usually brief and diminish as the eye becomes accustomed to the formulation.

Serious Reactions

While infrequent, persistent pain, changes in visual acuity, or signs of an allergic reaction involving significant swelling or intense redness should be addressed by a medical professional. If the initial mild discomfort evolves into prolonged irritation, usage should be paused.

Contraindications

Individuals with a documented sensitivity to the active compound or any of the inactive ingredients in the emulsion should avoid its use. It should also be approached with caution by those with active ocular infections.

Interaction Awareness

While topical application limits systemic exposure, the ingredient may interact with other eye drops or contact lens solutions. Please refer to the specific patient information leaflet provided with your medication to identify any substances that should not be used concurrently.

Treatment Consistency and Storage

Maintaining a consistent schedule is essential for the efficacy of this therapy, as the compound needs time to accumulate and modulate the immune response within the ocular tissue. Storage should be kept in a cool, dry area away from direct light to preserve the chemical stability of the emulsion. For detailed usage, frequency, and administration, refer to the specific medication's clinical information.

Glossary

Pharmacokinetics
The study of how the body absorbs, distributes, and processes a medicinal compound over time.
Immunomodulator
A substance that helps to adjust or regulate the activity of the immune system to reach a desired balance.
Ophthalmic
Relating to the anatomy, functions, or diseases of the eye.

Clinical Oversight and Use

This content provides an educational overview of Cyclomune and is not intended as medical advice or professional diagnosis. Please note that individual medications containing this ingredient differ in formulation strength, concentration, and specific administrative instructions. Responsibility for the application of clinical data rests with the practitioner. To ensure appropriate care, always consult the specific labeling of your prescribed medication and discuss your unique health context with a licensed healthcare professional in Hong Kong.

Categories